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(1)Blood Donations
The article below discusses recent research conducted in Denmark. The purpose was to determine how frequently viable bacteria were detected in donated blood units. Over 50% of the donated blood units had bacterial growth. The researchers conclude that insufficient methods to detect bacteria are being used and this contaminated blood is being transfused into patients. Discuss your thoughts on the article and include possible outcomes of this bacterial presence in donated blood. (PLEASE SEE ATTACHED FILE)
(2)Topic
Pediatric Acute-onset Neuropsychiatric Syndrome (PANS) is a clinical diagnosis given to children who have a dramatic – sometimes overnight – onset of neuropsychiatric symptoms including obsessions/compulsions or food restriction. They are often diagnosed with obsessive-compulsive disorder (OCD) or an eating disorder, but the sudden onset of symptoms separates PANS from these other disorders. In addition, they may have symptoms of depression, irritability, anxiety, and have difficulty with schoolwork. The cause of PANS is unknown in most cases but is thought to be triggered by infections, metabolic disturbances, and other inflammatory reactions.
Like PANS, children with Pediatric Autoimmune Neuropsychiatric Disorder Associated with Streptococcal Infections (PANDAS) have an acute onset – within 2 to 3 days – of neuropsychiatric symptoms, specifically OCD or tics (involuntary, purposeless movements). However, PANDAS patients test positive for a recent streptococcal infection, such as strep throat, peri-anal strep or scarlet fever. Like PANS patients, they also may suffer from uncontrollable emotions, irritability, anxiety and loss of academic ability and handwriting skills. Although PANDAS was identified as a medical syndrome more than a decade before PANS, it has been classified as a subset of PANS. To date, PANDAS is the only known subset of PANS, but we may discover more causes in the future.
This is an interesting new discovery in microbiology. What are your thoughts on this topic? What other diseases seem to be caused by an autoimmune response due to a microbial infection?
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