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Design or find a Supplement to remove Gadolinium Gd3+ from the human body. Detox. Chelation . It must have a High stability constant.

$250-750 USD

Cerrado
Publicado hace más de 8 años

$250-750 USD

Pagado a la entrega
Create a new organic supplement or find a existing supplment that will bind with Gd3+ ions Gadolinium in the human body and remove them from the body. EDTA is not good enough because it's stability constant is to close to Zinc. It is proposed that some other organic acids may have a very high affinity and stability constant for Gd3+ Malic Acid Galactaric Acid Clucaric Acid Is Cilantro effective. Need to test effects of different compounds on Gd3+ ions I believe nature already has this answer without having to resort to DTPA The Gd3+ ions left in the bodies after MRI Gadolinium contrast agents are mainly bound to Phosphorous. GdPO4 and the rest is Free Gd3+ ions. . Some may be bound to citrates, albumin, etc. I believe that GdPO4 logk = 12.5 but not sure. but, if the free Gd3+ ions are forming GdPO4H2O then the logk= 25 I think But we are not sure. DTPA has a conditional stability of 17.5. I am looking to find a better chelator then DTPA for Gd that is natural and I can sell as a supplement. Organic Acid compounds may have the ability to cross the BBB blood brain barrier as well and remove gd from the brain. Gd3Galactarate2 is proposed as having a logk = 30 Perhaps a Ca3Galactarate2 complex can be created to take as a supplment and exchange the Ca for Gd Also Gd-Malate with a composition of [login to view URL] has been shown to have a logk of 31 Could we create [login to view URL] and use as a chelator for Gd? These are some Ideas. We could need to do some testing.
ID del proyecto: 9003856

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Activo hace 8 años

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1 freelancer está ofertando un promedio de $750 USD por este trabajo
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Hi I am Msc in food biotechnology, microbiology and analytical chemistry. I have excellent knowledge of these subjects and 7years research and formulation experience. I have worked with food companies, cosmetics and pharma companies as a quality control and formulation researcher. I provide theoretical research based solutions to companies, students etc to develop new products and improve their already created products. I provide solutions in theory which my clients try out in their labs, if this method of working is acceptable looking forward to discussion. Regards, Suyash
$750 USD en 10 días
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Bandera de UNITED STATES
United States
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Miembro desde nov 30, 2015

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