Design our first clinical white paper

What are we making? (This is what the physical piece you are making will be. Consider the printing limitations, usage etc) The first white paper to support the clinical use of DoseMe, though we want it to be branded under our university program – The Dosing Institute ([login to view URL]). It will be used as a printed sales aid at sales calls and used to support the DoseMe and The Dosing Institute website library prompting users to register their details to receive the white paper via email (PDF format). As this is our first white paper, this will set the tone and template for future white papers that we will produce, therefore, we would like consideration to how this could roll out for future studies. We are also yet to produce any substantial collateral for the dosing institute, so will require consideration around the types of icons, graphics, colours, fonts and overall branding. Deliverables: ¬ 6pp leave behind (will be printed on 150 gsm matt) ¬ 6pp PDF (email ready) ¬ All original artwork / source files Primary Audiences Clinicians-administrator level - i.e. a layman with subject matter interest. Complicated statistics should be accompanied with a simple graphic explanation. Time on this paper will be limited so the key messages need to stand out. Target audiences ¬ Clinicians (ranging from infectious disease specialists, transplant surgeons, oncologists) ¬ Hospital Administrators (Hospital administrators from CTO’s through to Chief Medical Officers / CEOs) Objective Clinicians through to administrators are likely to be unaware that Bayesian dosing outperforms other statistical approaches in many conditions. Even if they are aware calculating area under a curve (AUC) is complicated and often replaced with simpler, less effective, proxies. Software available at a patient’s bedside and integrated into a clinicians workflow makes calculations of AUC possible, and makes precision dosing, that is, the ideal dose for each patient possible. It is a compelling reason for adoption of the DoseMe software in a clinical setting, in addition to the literature that supports Bayesian individualised dosing methods. Key messages The medical copywriter will focus on the four main key takeaways for this paper, and it is important these are highlighted visually as well: 1. DoseMe is more effective than conventional methods of AUC estimation (and therefore dose adjustment) for Tobramycin in patients with CF and practical for clinical setting 2. Only one assay result is required for accurate AUC estimation 3. Collection of samples is unrestricted and can be at patient-preferred times 4. DoseMe achieves higher accuracy and precision in calculating AUC using half as many laboratory results as the standard clinical method used at the RBWH (Kestral). Tone: ¬ Empowering and Sophisticated – we want to convey that we are helping clinicians to advance precision medicine through individualised dosing Imagery ¬ Precision medicine, advanced technology with a human element Mandatory ¬ The Dosing Institute logo ¬ The Dosing Institute website details ([login to view URL]) ¬ Quality number: WPTOB_TDI_05/17_001 Example preferred layout / design: We like the style of graphs, infographics and use of two columns [login to view URL] SUGGESTED IMAGE STYLES We would like to see a mixture of graphic vector elements and icons where appropriate, along with photographs to bring the document to life and give it a human element, whilst remaining like a clinical paper Tight deadline on this - we require it by Monday 15th May.